Gastroprotective and antioxidant potential of Glycyrrhiza glabra on experimentally induced gastric ulcers in albino mice

Ulcer is the lesion that pierces the muscularis mucosa which does not show the tendency to heal. Its etiology mainly includes imbalance between offensive and protective factors in mucosa of stomach such as mucosal barriers, cellular regeneration, acid-pepsin secretion, blood flow and epidermal growth factors (Lima et al., 2006). This imbalance usually happened as consequence of H. pylori infection and extensive usage of non-steroidal antiinflammatory drugs (NSAIDs) and clopidogral drugs; which ultimately resulted in peptic ulcer (Padussis and Pappas, 2010). ISSN: 2319-7706 Volume 4 Number 2 (2015) pp. 451-460 http://www.ijcmas.com